4Quant

Transforming images into information

Our vision is to offer customized stand-alone analysis to every microscopy user from cell biologists to petroleum engineers turning pictures into information in one click

4Quant

What we do

We are involved in the entire cycle from experiment design to measurement to analysis and interpretation. Pick and choose which components make the most sense for your needs.

We provide expertise in both static and dynamic X-ray imaging experiments on a wide variety of samples ranging from mouse bones to brain vasculature. We can help you design experiments, choose imaging modalities, scale up to large number of samples, and interpret the results in order to gain high quality, actionable information from imaging studies.
For existing studies, we provide the sample measurement as a service. We have years of experience working with X-ray tomography and can get the best performance from the instrumentation for 1 or 10,000 samples. We have priority access to the world-class imaging beamline, TOMCAT at the Swiss Light Source and can schedule experiments within weeks of the initial request. The versatility of the beamline enables high-resolution scans of incredibly high quality to performed in minutes and under the right circumstances rapidly evolving microstructures can be imaged fully in 3D more than 10 times per second.
We have powerful, scalable in-house developed software for processing and extracting quantitative information in a streamlined fashion for even very large data sets. The software is automatically tested and verified to ensure the highest level of reliability for the results. We have the latest infrastructure available for storing and interactively analyzing thousands of samples with millions of microstructures. With our network analysis tools we can even investigate complicated networks of cells or pores with 10s of millions of connections.
We always deliver as a final product a detailed report distilling a series of complicated analyses into clear, legible figures and tables with thorough explanations of every step taken so the results can be reliably, automatically reproduced.

Example Projects

We have worked on a number of projects in different fields varying from food research to bone microstructure. Below are a few selected projects which illustrate some of the capabilities we have.

4Quant

Porous microstructure of mouse cortical bone

For bone microstructure we have developed workflows for automatically aligning and measuring cortical bone samples [1]. Futhermore we can perform detailed structural analysis of cortical and trabecular bone. We can even examine the shape, distribution, and alignment of osteocyte lacunae and blood vessels to assess the cellular level affect of genes, treatments, and disease models [2]. A few of phenotype results are available for interactive exploration in a dashboard.

About Us

4Quant will be a Spin-off of the ETH Zurich and the Paul Scherrer Institut based on the PhD Thesis of Kevin Mader done in the X-Ray Microscopy Laboratory of Marco Stampanoni. We are funded by the Pioneer Fellowship of the ETH Zurich and a member of the ETH Innovation and Entrepreneurship Lab. Additionally, we are partnered with SLS Techno Trans AG which provides confidential, proprietary access to the beamline, instrumentation, and personnel resources of the Swiss Light Source.

Contact Information

We are located inside the Paul Scherrer Institut in Villigen, Switzerland. We can be reached by email at contact@4quant.com or by calling at +1.(503).610.8754